plasma cell lifespan quantitative systems pharmacology qsp matlab r2023b simbiology  (MathWorks Inc)

Journal: ACS Applied Bio Materials

Article Title: Zinc-Mediated Loading and Release of His-Tagged Recombinant Proteins in Self-Assembling Peptide Coacervates

doi: 10.1021/acsabm.5c02044

Figure Lengend Snippet: Modeling of pG-His elimination from the footpad depot. (A) One-compartmental model governed by first-order reaction kinetics and reversible binding between the cargo protein and metal–peptide coacervate; (B) fitting of imaging data to first-order elimination; (C) simulation of loading concentrations of the cargo protein (0–100 μg/mL) and prediction of AUC 0–∞ . Schematics were generated using MATLAB 2024.

Article Snippet: Computational simulations were performed using MATLAB 2024b SimBiology to model the elimination of dissociated proteins from Zn 2+ :EAKH6 coacervates at the site of injection (FP).

Techniques: Binding Assay, Imaging, Generated